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Medical Definition of Medial longitudinal bundle
1. A longitudinal bundle of fibres extending from the upper border of the mesencephalon into the cervical segments of the spinal cord, located close to the midline and ventral to the central gray matter; it is composed largely of fibres from the vestibular nuclei ascending to the motor neurons innervating the external eye muscles (abducens, trochlear, and oculomotor nuclei), and descending to spinal cord segments innervating the musculature of the neck. Synonym: fasciculus longitudinalis medialis, Collier's tract, medial longitudinal bundle, posterior longitudinal bundle. (05 Mar 2000)