|
Medical Definition of Maximum velocity
1. The maximum rate of an enzyme-catalyzed reaction that can be achieved by progressively increasing the substrate concentration at a given enzyme concentration; in cases of substrate inhibition, Vmax is an extrapolated value in the absence of such inhibition; Cf.: Michaelis-Menten equation. The maximum initial rate of shortening of a myocardial fibre that can be obtained under zero load; used to evaluate the contractility of the fibre. (05 Mar 2000)