Medical Definition of Macrolide
1.
A group of antibiotics produced by various strains of Streptomyces that have a complex macrocyclic structure.
They inhibit protein synthesis by blocking the 50S ribosomal subunit. Include erythromycin, carbomycin. Used clinically as broad spectrum antibiotics, particularly against gram-positive bacteria.
This entry appears with permission from the Dictionary of Cell and Molecular Biology
(11 Mar 2008)
Lexicographical Neighbors of Macrolide
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