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Medical Definition of Loop excision
1. A diagnostic and therapeutic gynecological surgical technique for removing dysplastic cells from the cervix. In this office procedure conducted with the aid of colposcopy, a small wire loop is used to excise visible patches of cervical intraepithelial neoplasia. Like cauterization, cryosurgery, and CO2 laser procedures, loop excision can be done with local anaesthetic, and is an uncomplicated, relatively inexpensive way of removing dysplastic cells; in addition, it provides material for biopsy. It is not advised for cases of severe dysplasia or carcinoma in situ, which are better addressed by cervical conization, an inpatient procedure. Synonym: loop resection. (05 Mar 2000)