Definition of Long-term potentiation

1. Noun. (neuroscience) A long-lasting (hours ''in vitro'', weeks to months ''in vivo'') increase, typically in amplitude, of the response of a postsynaptic neuron to a particular pattern of stimuli from a presynaptic neuron. ¹

¹ Source: wiktionary.com

Medical Definition of Long-term potentiation

1. Increase in the strength of transmission at a synapse with repetitive use that lasts for more than a few minutes. As a form of long term synaptic plasticity it is important as a possible cellular mechanism for the basis of learning and memory storage. It has been studied most extensively at excitatory synapses onto principal neurons of the hippocampus where it was first demonstrated. Selective inhibition of NMDA receptor channels has been shown to block long-term potentiation and to block spatial learning. (12 Dec 1998)

Lexicographical Neighbors of Long-term Potentiation

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long-sufferance
long-suffering
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long-tail boats
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long-tailed pangolin
long-tailed porcupine
long-tailed tit
long-tailed weasel
long-term
long-term care
long-term memory
long-term nonprogressor
long-term potentiation (current term)
long-term productivity
long-term survival
long-terminal repeat
long-tongue
long-vowel mark
long-vowel marks
long-wearing
long-winded
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long-windedness
long-wool
long-wooled
long abductor muscle of thumb

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