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Medical Definition of Limb bud
1. The limbs of vertebrates start as outpushings of mesenchyme surrounded by a simple epithelium. The distal region is referred to as the progress zone. There has been extensive study of positional information within the limb bud that determines, for example: the proximal distal pattern of bone development and the anterior posterior specification of digits. This entry appears with permission from the Dictionary of Cell and Molecular Biology (11 Mar 2008)
Lexicographical Neighbors of Limb Bud
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