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Medical Definition of Leukoblast
1. An immature white blood cell that is transitional between the lymphoidocyte (or the myeloblast of Naegeli and Downey) and the promyelocyte; the cytoplasm is polychromatophilic or slightly acidophilic and, as compared with the lymphoidocyte, the nuclear network of chromatin is thicker and the nucleoli less distinct. Synonym: proleukocyte. Origin: Leuko-+ G. Blastos, germ (05 Mar 2000)