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Medical Definition of Lepromin test
1. A test utilizing an intradermal injection of a lepromin, such as the Dharmendra antigen or Mitsuda antigen, to classify the stage of leprosy based on the lepromin reaction, such as the Fernandez reaction or Mitsuda reaction; it differentiates tuberculoid leprosy, in which there is a positive delayed reaction at the injection site, from lepromatous leprosy, in which there is no reaction (i.e., a negative test result) despite the active malignant Mycobacterium leprae infection; the test is not diagnostic, since normal uninfected persons may react. (05 Mar 2000)