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Medical Definition of Lepra cells
1. Distinctive, large, mononuclear phagocytes (macrophages) with a foamlike cytoplasm, and also poorly staining saclike structures resulting from degeneration of such cell's, observed characteristically in leprous inflammatory reactions; indistinct staining results from numerous, fairly closely packed leprosy bacilli, which are acid-fast and resistant to staining by ordinary methods but may be vividly demonstrated by acid-fast staining procedures. (05 Mar 2000)