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Medical Definition of Lateral column
1. A slight protrusion of the gray matter of the spinal cord into the lateral funiculus of either side, especially marked in the thoracic region where it encloses preganglionic motor neurons of the sympathetic division of the autonomic nervous system; it corresponds to the lateral horn appearing in transverse sections of the spinal cord. See: gray columns. Synonym: columna lateralis, lateral column of spinal cord. (05 Mar 2000)