Lexic.us

Definition of Ketamine

1. Noun. A general anesthetic and tranquilizer (not a barbiturate) that is administered intravenously or intramuscularly; used mainly by veterinarians or for minor surgery with geriatric or pediatric patients; taken in large doses it causes hallucinations similar to those associated with the use of PCP.

Definition of Ketamine

1. Noun. a pain-killing drug and anaesthetic ¹

¹ Source: wiktionary.com

Definition of Ketamine

1. a general anesthetic [n -S]

Medical Definition of Ketamine

1. A cyclohexanone derivative used as an intravenous anaesthetic. Ketamine produces a dissociative anaesthesia in which the patient is not asleep but does not respond appropriately to environmental stimuli, including pain. Upon revival, the patient does not remember what occurred under the influence of the drug. Its mechanism of action is not well understood, but ketamine can block nmda receptors (receptors, n-methyl-d-aspartate) and may interact with sigma receptors. Pharmacological action: anaesthetics, dissociative, excitatory amino acid antagonists. Chemical name: Cyclohexanone, 2-(2-chlorophenyl)-2-(methylamino)-, (+-)- (12 Dec 1998)

Lexicographical Neighbors of Ketamine

Literary usage of Ketamine

Below you will find example usage of this term as found in modern and/or classical literature:

1. Proceedings of the Society for Experimental Biology and Medicine (1903)
"a given male rat, ketamine anesthesia is acceptable. For studies in which anesthetized rats might be desirable, ketamine is clearly preferable to other ..."

2. Date Rape Drugs: Hearing Before the Committee on Commerce, U.S. House of edited by Fred Upton (2000)
"ketamine is difficult to synthesize and there have been no reports of its clandestine manufacture All of the ketamine encountered by law enforcement to date ..."

3. Code of Federal Regulations by Food and Drug Administration (FDA) Staff (2005)
"Each milliliter contains ketamine hydrochloride equivalent to 100 milligrams (mg) ketamine base activity. (b) Sponsors. See Nos. ..."

4. Harmful Non-Indigenous Species in the United States (1994)
"The NMDA antagonist ketamine produced dose-related ethanol-like effects in recently ... The response to ketamine was rated significantly more similar to the ..."

5. Pediatric Drug Research: Studies Conducted Under Best Pharmaceuticals for by Marcia Crosse (2007)
"ketamine is listed in the Federal Register as a drug in need of study in children ... Because of data demonstrating that ketamine enhances cell death in the ..."

6. Pulse Check: National Trends in Drug Abuse: Summer 1998 by Barry M. McCaffrey (1999)
"ketamine, or "Special K" continues to gain popularity. ketamine, an animal tranquilizer that has legitimate uses in veterinary medicine, was first reported ..."

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