Lexic.us

Definition of Isoproterenol

1. Noun. Drug (trade name Isuprel) used to treat bronchial asthma and to stimulate the heart.

Definition of Isoproterenol

1. Noun. (medicine) An aromatic amine, used as a sympathomimetic bronchodilator ¹

¹ Source: wiktionary.com

Definition of Isoproterenol

1. [n -S]

Medical Definition of Isoproterenol

1. Synthetic beta-adrenergic agonist, causes peripheral vasodilation, bronchodilation and increased cardiac output. It possesses the cardiac excitatory, but not the vasoconstrictor, actions of epinephrine. Chemically it differs from epinephrine in having an isopropyl group replacing the methyl group attached to the nitrogen atom; used in the treatment of bronchial asthma and heart block, including Adams-Stokes attacks. Pharmacologic action: Pure beta-adrenergic agonist. Inotropic and chronotropic effects increase heart rate and cardiac output. Blood pressure usually falls due to vasodilation. Uses: Can be used to treat complete heart block and atropine refractory bradycardia, but it is not the drug of choice for either condition. Dose: 2-10 mcg/min Start at 2 mcg/min and titrate to effect. Rarely need more than 10 mcg/min Potential complications: arrhythmias, vasodilation causes hypotension and reduced coronary perfusion leading to myocardial ischemia, at low doses it may be helpful for symptomatic bradycardias, but at higher doses it is harmful. Note: Other inotropic agents that cause less arrhythmias and ischemia are usually preferred Chemical name: 3,4-Dihydroxy-alpha-[(isopropylamino)methyl]benzyl alcohol hydrochloride. Synonym: isoprenaline hydrochloride, isopropylarterenol hydrochloride. (15 Mar 2000)

Lexicographical Neighbors of Isoproterenol

Literary usage of Isoproterenol

Below you will find example usage of this term as found in modern and/or classical literature:

1. Proceedings of the Society for Experimental Biology and Medicine (1903)
"Apparently, not h of the isoproterenol escaped inacti- by the liver to ... :r the infusion of isoproterenol was ted, the hepatic venous plasma [K] ed the ..."

2. Science by American Association for the Advancement of Science (1883)
"The dependence of the hyper polarizing effect on a low external concentration of potassium is similar to that observed with isoproterenol. ..."

3. A Lifelong Passion: Nicholas and Alexandra: Their Own Story by Andrei Maylunas (2005)
"isoproterenol elicited cardiac augmentations when injected into, on average, ... The responses elicited by isoproterenol injections were eliminated when the ..."

4. Code of Federal Regulations, Title 21, Food and Drugs, PT. 200-299, Revised by Food and Drug Administration (FDA) Staff (2005)
"In addition, sudden unexpected deaths have been associated with the excessive use of isoproterenol inhalation preparations. The mechanism of these deaths ..."

5. Chronic Fatigue Syndrome: Information for Physicians edited by Barry Leonard (1998)
"In contrast, no control subject had a positive response to upright tilt in •the absence of isoproterenol, and all con- . trois remained ..."

6. Mammalian Models for Research on Aging by Bennett J. Cohen, Institute Of Laboratory Animal Resources, National Research Council Staff (1981)
"Metabolic and histopathologic changes in arteriosclerotic versus non-arteriosclerotic rats following isoproterenol-induced myocardial infarction with ..."

7. Guidelines for the Diagnosis and Management of Asthma by DIANE Publishing Company (1996)
"Matson JR, Loughlin JM, Strunk RC: Myocardia ischemia complicating the use of isoproterenol in asthmatic children. J Pediatr 1978; 92:776-778. 32. ..."

8. Proceedings of the Society for Experimental Biology and Medicine (1903)
"Apparently, not h of the isoproterenol escaped inacti- by the liver to ... :r the infusion of isoproterenol was ted, the hepatic venous plasma [K] ed the ..."

9. Science by American Association for the Advancement of Science (1883)
"The dependence of the hyper polarizing effect on a low external concentration of potassium is similar to that observed with isoproterenol. ..."

10. A Lifelong Passion: Nicholas and Alexandra: Their Own Story by Andrei Maylunas (2005)
"isoproterenol elicited cardiac augmentations when injected into, on average, ... The responses elicited by isoproterenol injections were eliminated when the ..."

11. Code of Federal Regulations, Title 21, Food and Drugs, PT. 200-299, Revised by Food and Drug Administration (FDA) Staff (2005)
"In addition, sudden unexpected deaths have been associated with the excessive use of isoproterenol inhalation preparations. The mechanism of these deaths ..."

12. Chronic Fatigue Syndrome: Information for Physicians edited by Barry Leonard (1998)
"In contrast, no control subject had a positive response to upright tilt in •the absence of isoproterenol, and all con- . trois remained ..."

13. Mammalian Models for Research on Aging by Bennett J. Cohen, Institute Of Laboratory Animal Resources, National Research Council Staff (1981)
"Metabolic and histopathologic changes in arteriosclerotic versus non-arteriosclerotic rats following isoproterenol-induced myocardial infarction with ..."

14. Guidelines for the Diagnosis and Management of Asthma by DIANE Publishing Company (1996)
"Matson JR, Loughlin JM, Strunk RC: Myocardia ischemia complicating the use of isoproterenol in asthmatic children. J Pediatr 1978; 92:776-778. 32. ..."

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