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Medical Definition of Insular cortex
1. 1. An oval region of the cerebral cortex overlying the extreme capsule, lateral to the lenticular nucleus, buried in the depth of the fissura lateralis cerebri (sylvian fissure). Synonym: insular area, insular cortex, island of Reil. Synonym: island. 3. Any circumscribed body or patch on the skin. Origin: L. Island (05 Mar 2000)