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Medical Definition of Inositol trisphosphate
1. Inositol 1, 4, 5 trisphosphate is important as a second messenger. It is released from phosphatidyl inositol bisphosphate by the action of a specific phospholipase C enzyme (PLC_) and binds to and activates a calcium channel in the endoplasmic reticulum. This entry appears with permission from the Dictionary of Cell and Molecular Biology (11 Mar 2008)