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Definition of Inosine
1. Noun. A nucleoside that is formed by the deamination of adenosine; used in kidney transplantation to provide a temporary source of sugar.
Generic synonyms: Nucleoside
Definition of Inosine
1. a compound of hypoxanthine and ribose [n -S]
Medical Definition of Inosine
1. The fifth base of nucleic acids. Important because it fails to form specific pair bonds with the other bases. In transfer RNAs, this property is used in the anticodon to allow matching of a single tRNA to several codons. PCR perfomed with primers containing inosine tolerates a limited degree of mismatch between primer and template, useful in homology probing. This entry appears with permission from the Dictionary of Cell and Molecular Biology (11 Mar 2008)