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Medical Definition of Immediate early gene
1. Class of genes whose expression is low or undetectable in quiescent cells, but whose transcription is activated within minutes after extracellular stimulation such as addition of a growth factor. C fos and c myc proto-oncogenes were among the first IEG's to be identified. Many IEG's encode transcription factors and therefore have a regulatory function. This entry appears with permission from the Dictionary of Cell and Molecular Biology (11 Mar 2008)
Lexicographical Neighbors of Immediate Early Gene
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