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Definition of Idiotype
1. Noun. (immunology) A characteristic shared by a group of immunoglobulin or T cell receptor molecules, based on the antigen binding specificity of their variable region ¹
¹ Source: wiktionary.com
Definition of Idiotype
1. a structure of an antibody [n -S]
Medical Definition of Idiotype
1. The antigenic specificites defined by the unique sequences (idiotopes) of the antigen combining site. Thus anti-idiotype antibodies combine with those specific sequences, may block immunological reactions and may resemble the epitope to which the first antibody reacts. This entry appears with permission from the Dictionary of Cell and Molecular Biology (11 Mar 2008)
Lexicographical Neighbors of Idiotype
Literary usage of Idiotype
Below you will find example usage of this term as found in modern and/or classical literature:
1. Understanding the Immune System by Lydia Woods Schindler (1991)
"More precisely, the variable region contains a number of antigen-like segments,
and these are known collectively as an idiotype. ..."
2. Proceedings of the Society for Experimental Biology and Medicine (1903)
"Athough an increase in affinity of the anti-idiotype produced after a single
booster injection is consistent with the general characteristic of a secondary ..."
3. Bulletin of the American Museum of Natural History by American Museum of Natural History (1919)
"idiotype See No. 18385. The holotype of this species came from the ... therefore the
specimen in the Collection is an idiotype. 18539. ..."
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