Medical Definition of Hypoplasia of the thymus and parathyroids

1. Also known as the digeorge syndrome (dgs), this disorder is characterised by (1) low blood calcium levels (hypocalcaemia) due to underdevelopment (hypoplasia) of the parathyroid glands needed to control calcium; (2) underdevelopment (hypoplasia) of the thymus, an organ behind the breastbone in which lymphocytes mature and multiply; and (3) defects of the outflow tracts from the heart. most cases of dgs are due to a microdeletion in chromosome band 22q11.2. A small number of cases have defects in other chromosomes, notably 10p13. Named after the american paediatric endocrinologist angelo digeorge. Another name for dgs is the third and fourth pharyngeal pouch syndrome (since the faulty structures in dgs are embryologically derived from the third and fourth pharyngeal pouches). (12 Dec 1998)

Lexicographical Neighbors of Hypoplasia Of The Thymus And Parathyroids

hypophysiotropic
hypophysiotropic hormone
hypophysis
hypophysis cerebri
hypophysis sicca
hypophysitis
hypopiesis
hypopigmentation
hypopigmentations
hypopigmented
hypopituitarism
hypopituitarisms
hypopituitary
hypoplasia
hypoplasia of right ventricle
hypoplasia of the thymus and parathyroids (current term)
hypoplasias
hypoplasic
hypoplastic
hypoplastic anaemia
hypoplastic anemia
hypoplastic dwarf
hypoplastic heart
hypoplastic left heart syndrome
hypoplastra
hypoplastron
hypoplastrons
hypoploid
hypoploids

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