Lexic.us

Definition of Hybridisation

1. Noun. (genetics) the act of mixing different species or varieties of animals or plants and thus to produce hybrids.

Definition of Hybridisation

1. Noun. (alternative form of hybridization) ¹

¹ Source: wiktionary.com

Medical Definition of Hybridisation

1. The process of joining two complementary strands of DNA or one each of DNA and RNA to form a double-stranded molecule. Technique in which single stranded nucleic acids are allowed to interact so that complexes or hybrids, are formed by molecules with sufficiently similar, complementary sequences. By this means the degree of sequence identity can be assessed and specific sequences detected. The hybridisation can be carried out in solution or with one component immobilised on a gel or, most commonly, nitrocellulose paper. Hybrids are detected by various means: visualisation in the electron microscope, by radioactively labelling one component and removing noncomplexed DNA or by washing or digestion with an enzyme that attacks single stranded nucleic acids and finally estimating the radioactivity bound. Hybridisations are done in all combinations: DNA DNA (DNA can be rendered single stranded by heat denaturation), DNA RNA or RNA RNA. In situ hybridisations involve hybridising a labelled nucleic acid (often labelled with a fluorescent dye) to suitably prepared cells or histological sections. This is used particularly to look for specific transcription or localisation of genes to specific chromosomes (FISH analysis). The mating of individuals from different species or sub-species. (13 Oct 1997)

Lexicographical Neighbors of Hybridisation

Literary usage of Hybridisation

Below you will find example usage of this term as found in modern and/or classical literature:

1. Journal of the Royal Horticultural Society by Royal Horticultural Society (Great Britain). (1900)
"hybridisation IN THE UNITED STATES. By Professor LH BAILEY, Cornell University, Ithaca, USA IN considering the status of hybridisation in any country two ..."

2. The Cell; Outlines of General Anatomy and Physiology: Outlines of General by Oscar Hertwig, Henry Johnstone Campbell (1895)
"Bastard Formation, or hybridisation. The opposite of self-fertilisation and in-breeding is hybridisation. By this is meant the union of several products of ..."

3. Report of the Annual Meeting (1904)
"Recent Experiments in the hybridisation of Orchids. By CHARLES C. HURST. Recent Progress in Orchid hybridisation. First hybrid raised in 1866. ..."

4. Peruvian Bark: A Popular Account of the Introduction of Chinchona by Clements Robert Markham (1880)
"Chinchona hybridisation. prosperously from the time of my visit to the ... about the same time an important question arose with reference to hybridisation. ..."

5. Text-book of Botany, Morphological and Physical by Julius Sachs (1882)
"Among Cryptogams only a few instances of hybridisation are known with ... has collected the results of many thousand experiments on hybridisation made by ..."

6. Proceedings of the Cambridge Philosophical Society by Cambridge Philosophical Society (1906)
"Experiments on the hybridisation of Barleys. By R H. BIFFEN, MA, Emmanuel College. [Read 12 February 1906.] The cultivated barleys form a group of ..."

7. A Practical Guide to Garden Plants by John Weathers (1901)
"FERTILISATION AND hybridisation them to be really modified leaves) they are ... FERTILISATION AND hybridisation Since the functions of the stamens and ..."

8. Agricultural Botany: Theoretical and Practical by John Percival (1921)
"(v) hybridisation is usually, though not always, reciprocal: if the pollen of a species A is effective upon the ovules of another species B, the pollen of B ..."

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