2. Noun. (US slang Southeast) A big person, usually a man; a person who has size comparable to that of a horse. ¹
3. Noun. (US slang Southeast) Slang term of address for a man. ''What's up, hoss?'' ¹
4. Noun. (slang) A well-respected person. ¹
5. Noun. (US slang Northwest) A Car. ¹
¹ Source: wiktionary.com
Definition of Hoss
1. a horse [n -ES]