¹ Source: wiktionary.com
Definition of Gnotobiotic
1. [adj]
Medical Definition of Gnotobiotic
1. Denoting germ-free or formerly germ-free organisms in which the composition of any associated microbial flora, if present, is fully defined. Origin: see gnotobiota (05 Mar 2000)
Lexicographical Neighbors of Gnotobiotic
Literary usage of Gnotobiotic
Below you will find example usage of this term as found in modern and/or classical literature:
1. Ending the War Metaphor: The Changing Agenda for Unraveling the Host-Microbe by Forum on Microbial Threats, Institute of Medicine (U.S.) (2006)
"Studies in gnotobiotic mice have indicated that there is specific signalling
between the commensal bacterium B. thetaiotaomicron and its host. ..."
2. Manual of Microbiologic Monitoring of Laboratory Animals edited by Kim Waggie (1994)
"Pneumonia due to mycoplasma in gnotobiotic mice. ... Mycoplasma pulmonis infection
in gnotobiotic and conventional mice: Aspects of pathogenicity including ..."
3. Mammalian Models for Research on Aging by Bennett J. Cohen, Institute Of Laboratory Animal Resources, National Research Council Staff (1981)
"The gnotobiotic Norway rat (Rattus norvegicus) has been used as a model for ...
gnotobiotic rats innoculated orally with some kinds of bacteria from ..."
4. Treating Infectious Diseases in a Microbial World: Report of Two Workshops by National Research Council (2006)
"In animal-microorganism interactions, studies with germfree and gnotobiotic mice
over the last several years have greatly expanded our understanding of the ..."
5. Diarrhea and Malnutrition: Interactions, Mechanisms, and Interventions by Lincoln C. Chen, Nevin S. Scrimshaw (1983)
"... and in experimental infection of gnotobiotic, colostrum-deprived calves with
human rotaviruses.79 In the calf model, denuded villus tips are replaced ..."
6. Guidelines for the Humane Transportation of Research Animals by National Research Council (U. S.) (2006)
"For gnotobiotic animals (animals whose microfauna and microflora are known in
their entirety) and immuno- compromised animals ..."
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