Medical Definition of Giant cell

1. A cell of large size, often with many nuclei. They are multinucleated masses produced by the fusion of many cells. They are often associated with viral infections. In AIDS, they are induced when the envelope glycoprotein of HIV binds to the CD4 antigen of uninfected neighboring T4 cells. The resulting syncytium leads to cell death and thus may account for the cytopathic effect of the virus. (18 Jul 2002)

Lexicographical Neighbors of Giant Cell

giant anteater
giant anteaters
giant armadillo
giant armadillos
giant axon
giant axonal neuropathy
giant bamboo
giant cane
giant cell (current term)
giant cell aortitis
giant cell arteritis
giant cell astrocytoma
giant cell carcinoma
giant cell carcinoma of thyroid gland
giant cell epulis
giant cell fibroma
giant cell granuloma
giant cell hepatitis
giant cell hyaline angiopathy
giant cell monstrocellular sarcoma of Zulch
giant cell myeloma
giant cell pneumonia
giant cell sarcoma

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