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Medical Definition of Germinal streak
1. An ectodermal ridge in the midline at the caudal end of the embryonic disk from which arises the intraembryonic mesoderm; achieved by inward and then lateral migration of cells; in human embryos, it appears on day 15 and gives a cephalocaudal axis to the developing embryo. Synonym: germinal streak. (05 Mar 2000)