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Medical Definition of Ganglion isthmi
1. A median, unpaired, ovoid cell group at the base of the midbrain tegmentum between the cerebral peduncles; it receives the retroflex fasciculus from the habenula, and projects to the raphe region (raphe nuclei) and periaqueductal gray substance of the midbrain. Synonym: nucleus interpeduncularis, ganglion isthmi, Gudden's ganglion, intercrural ganglion, interpeduncular ganglion. (05 Mar 2000)