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Definition of Game over
1. Phrase. (video games) A message that appears on the screen of a computer or video game when all of the player's lives have been lost and the game must be started again from a checkpoint, the time runs out, or save point, or when the game has been successfully completed. ¹
2. Phrase. (context: by extension) The end of some ongoing situation due to either failure or success. ¹
¹ Source: wiktionary.com