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Definition of Gain-
1. Prefix. Prefix meaning "against", "contrary to", "in opposition to", "counter-". ¹
2. Prefix. Prefix denoting reciprocal action; "in return"; "counter-". ¹
3. Prefix. Prefix denoting restoration or a return to a previous state; "back again". ¹
4. Prefix. Prefix denoting repetition; "over again"; "anew"; again-. ¹
¹ Source: wiktionary.com