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Medical Definition of Formyltetrahydrofolates
1. Tetrahydrofolates which are substituted by a formyl group at either the nitrogen atom in the 5 position or the nitrogen atom in the 10 position. N(5)-formyltetrahydrofolate is leukovorin (citrovorum factor) while n(10)-formyltetrahydrofolate is an active coenzyme which functions as a carrier of the formyl group in a number of enzymatic reactions. (12 Dec 1998)