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Medical Definition of Foramen subseptale
1. In the embryonic heart, the temporary opening between right and left atria situated between the lower margin of the septum primum and the atrioventricular canal cushions, in an adult heart, the abnormal persistence of the so-named communication which is normal in young embryos. Synonym: foramen subseptale, ostium primum, primary interatrial foramen. (05 Mar 2000)