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Medical Definition of Filgrastim
1. A haematopoietic growth factor which promotes proliferation and maturation of neutrophil granulocytes. Clinically it is effective in decreasing the incidence of febrile neutropenia in patients with non-myeloid malignancies receiving myelosuppressive therapy or in reducing the duration of neutropenia and neutropenia-related clinical sequelae in patients with non-myeloid malignancies undergoing myeloblastive chemotherapy followed by bmt. It has also been used in aids patients with cmv retinitis being treated with ganciclovir. (gelman cr, rumack bh & hess aj (eds): drugdex(r) system.micromedex, inc., englewood, colourado (edition expires 11/30/95)) (12 Dec 1998)