Medical Definition of Filamin
1.
A protein that binds to F actin, cross linking it to form an isotropic network, the binding does not require Ca. It was originally isolated from smooth muscle and is a homodimer 2 x 250 kD. Similar to actin binding protein (ABP) from leucocytes.
This entry appears with permission from the Dictionary of Cell and Molecular Biology
(11 Mar 2008)
Lexicographical Neighbors of Filamin
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