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Medical Definition of Fibrinopeptide a
1. Two small peptide chains removed from the n-terminal segment of the alpha chains of fibrinogen by the action of thrombin during the blood coagulation process. Each peptide chain contains 18 amino acid residues. In vivo, fibrinopeptide a is used as a marker to determine the rate of conversion of fibrinogen to fibrin by thrombin. (12 Dec 1998)