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Medical Definition of Erythraemic myelosis
1. A neoplastic process involving the erythropoietic tissue, characterised by anaemia, irregular fever, splenomegaly, hepatomegaly, haemorrhagic disorders, and numerous erythroblasts in all stages of maturation (with disproportionately large numbers of less mature forms) in the circulating blood; postmortem studies reveal primitive erythroblasts and reticuloendothelial cells, not only in haemopoietic organs, but also in the kidneys, adrenal glands, and other sites. Acute and chronic forms are recognised, but in the latter there is less prominence of the immature cells; the former is also called Di Guglielmo's disease and acute erythraemia. (05 Mar 2000)