Medical Definition of Epitope library
1.
Large collection (hundreds of millions) of peptides each encoded by a randomly mutated piece of DNA in a phage genome and expressed on the surface of that bacteriophage, sometimes as an N terminal extension of a coat protein. Particular phages can be selected by a binding assay and since the peptide has its encoding DNA associated with it sequencing is straightforward.
This entry appears with permission from the Dictionary of Cell and Molecular Biology
(11 Mar 2008)
Lexicographical Neighbors of Epitope Library
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