Lexic.us

Definition of Epinephrine

1. Noun. A catecholamine secreted by the adrenal medulla in response to stress (trade name Adrenalin); stimulates autonomic nerve action.

Definition of Epinephrine

1. Noun. (hormone) Adrenaline: a catecholamine hormone secreted by the adrenal gland in response to stress (when it stimulates the autonomic nervous system). ¹

2. Noun. (neurotransmitter) A neurotransmitter which is synthesized from norepinephrine. ¹

¹ Source: wiktionary.com

Definition of Epinephrine

1. [n -S]

Medical Definition of Epinephrine

1. A cardiac drug used for cardiac arrest from ventricular fibrillation, ventricular tachycardia, asystole, or pulseless electrical activity; extreme hypotension; bradycardia and heart block. Pharmacologic action: 1. Beneficial mainly due to alpha stimulation - increases systemic vascular resistance and improves coronary and cerebral blood flow. 2. Value of beta stimulation is controversial - increases myocardial electrical activity and strength of contraction, but also increases myocardial oxygen requirements and automaticity. Dose: Cardiac arrest: Recommended: 1 mg IV push every 3-5 min Intermediate: 2-5 mg IV push every 3-5 min Escalating: 1 mg, 3 mg, 5 mg IV push 3 min apart High: 0.1 mg/kg IV push every 3-5 min Continuous infusion for bradycardia and severe hypotension: 2 - 10 mcg/min. Epinephrine can be delivered via the endotracheal tube. Increase dose 2-2.5 times IV dose. Potential complications: hypertension and tachycardia, arrhythmias, especially ventricular ectopy, myocardial ischemia. Synonym: adrenaline. (15 Mar 2000)

Lexicographical Neighbors of Epinephrine

Literary usage of Epinephrine

Below you will find example usage of this term as found in modern and/or classical literature:

1. The Journal of Experimental Medicine by Rockefeller University, Rockefeller Institute, Rockefeller Institute for Medical Research (1920)
"Bainbridge and Parkinson (2) found by staining methods that epinephrine entirely disappeared from the suprarenal glands in cases of death from acute ..."

2. Physiology and biochemistry in modern medicene by John James Rickard Macleod (1922)
"THE ENDOCRINE ORGANS, OR DUCTLESS GLANDS stances in the blood other than epinephrine may not be responsible for the cardiac changes. ..."

3. Biochemic Drug Assay Methods by Paul Stewart Pittenger (1914)
"epinephrine acts peripherally on a variety of structures probably by ... The contraction of the vessels due to epinephrine can be shown by applying it to a ..."

4. Practical Standardization by Chemical Assay of Organic Drugs and Galenicals by Albert Brown Lyons (1920)
"There has not as yet been devised any method of extracting epinephrine ... The color produced if the sample contains 0.2 percent of epinephrine is matched ..."

5. Proceedings of the Society for Experimental Biology and Medicine (1903)
"The addition of epinephrine to the incubation medium of fat cells from both obese and nonobese control mice increased FFA release, ..."

6. Pharmacology and Therapeutics for Students and Practitioners of Medicine by Horatio Charles Wood (1916)
"As mentioned above, the effects of epinephrine are the same as those of stimulation of the sympathetic nerve, and whether contraction or relaxation follows ..."

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