Medical Definition of Dox-sl
1.
A chemotherapy agent used for Kaposi's sarcoma consisting of a preparation of doxorubicin encapsulated in liposomes which deliver significantly greater quantities of doxorubicin to the KS lesions while reducing the drug's side effects. DOX-SL incorporates so-called stealth liposomes, whose polyethylene glycol (PEG) coating gives them still greater stability in the bloodstream.
Side effects include nausea, vomiting, stomatitis, diarrhoea and hair loss. DOX-SL causes a significant amount of neutropenia, which can be managed with G-CSF.
(10 Oct 1997)
Lexicographical Neighbors of Dox-sl
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