Lexic.us

Definition of Disulfiram

1. Noun. A drug (trade name Antabuse) used in the treatment of alcoholism; causes nausea and vomiting if alcohol is ingested.

Definition of Disulfiram

1. Noun. (medicine) A drug, ''1-(diethylthiocarbamoyldisulfanyl)- N,N-diethyl-methanethioamide'', used to treat chronic alcoholism ¹

¹ Source: wiktionary.com

Definition of Disulfiram

1. [n -S]

Medical Definition of Disulfiram

1. A carbamate derivative used as an alcohol deterrent. It is a relatively nontoxic substance when administered alone, but markedly alters the intermediary metabolism of alcohol. When alcohol is ingested after administration of disulfiram, blood acetaldehyde concentrations are increased, followed by flushing, systemic vasodilation, respiratory difficulties, nausea, hypotension, and other symptoms (acetaldehyde syndrome). The intensity and duration of symptoms vary greatly from individual to individual. Pharmacological action: alcohol deterrents. Chemical name: Thioperoxydicarbonic diamide (((H2N)C(S))2S2), tetraethyl- (12 Dec 1998)

Lexicographical Neighbors of Disulfiram

Literary usage of Disulfiram

Below you will find example usage of this term as found in modern and/or classical literature:

1. Overview of Addiction Treatment Effectiveness by Mim J. Landry (1996)
"Within the substantial body of research on disulfiram, there have been over 20 well-designed and controlled studies, and they are nearly evenly divided with ..."

2. Treatment for Stimulant Use Disorders edited by Richard A. Rawson, Rose M. Urban (2000)
"Figure 4-8 for related research on disulfiram therapy. ... Figure 4-8 Related Research: disulfiram Therapy An uncontrolled study by Higgins et al. ..."

3. Motivational Enhancement Therapy Manual: A Clinical Research Guide for by William R. Miller (1994)
"If clients are planning to use disul- firam as part of their postdischarge plans, it is important to explore how the disulfiram will help and what role it ..."

4. Alcohol and the Brain (1993)
"Blockade of this enzyme may result in higher dopamine Medications To Produce Aversive Drug Interaction disulfiram (Antabuse) is the classic agent in this ..."

5. Alcohol and Health: Seventh Special Report to the Us Congress by Louis Sullivan (1997)
"Many of the complexities surrounding the therapeutic use of disulfiram were addressed ... 1986) found that disulfiram reduced the frequency of drinking in a ..."

6. Assessing Alcohol Problems: A Guide for Clinicians and Researchers by John P. Allen, Megan Columbus (1997)
"For example, disulfiram implants, although not used in the United States, are a treatment modality with more evidence of effectiveness than oral disulfiram ..."

7. Research on Alcohol and Alcoholism (1993)
"The researchers found that disulfiram did not help to delay a return to drinking, ... disulfiram administration was unsupervised in this study. ..."

8. Preventing HIV Infection Among Injecting Drug Users in High Risk Countries by Institute of Medicine (U. S.), National Academies Press (U.S. (2007)
"Several studies suggest that disulfiram, an aversive drug therapy used to help ... A number of randomized controlled trials of disulfiram support its ..."

Other Resources: