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Medical Definition of Differentiation antigen
1. Any large structural macromolecule that can be detected by immune reagents and that also is associated with the differentiation of a particular cell type or types. Many cells can be identified by their possession of a unique set of differentiation antigens. There should be no implication that the antigens cause differentiation. This entry appears with permission from the Dictionary of Cell and Molecular Biology (11 Mar 2008)