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Definition of Depyrimidination
1. Noun. (context: chemistry biology) A process in which the chemical bond linking a pyrimidine (cytosine or thymine) to a deoxyribose sugar breaks spontaneously. It occurs at a lower rate compared to depurination with only 500 cytosine and thymine bases lost per cell per day in a typical mammalian cell. ¹
¹ Source: wiktionary.com