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Definition of Denaturation
1. [n -S]
Medical Definition of Denaturation
1. Reversible or irreversible loss of function in proteins and nucleic acids resulting from loss of higher order secondary, tertiary or quaternary structure) produced by nonphysiological conditions of pH, temperature, salt or organic solvents. This entry appears with permission from the Dictionary of Cell and Molecular Biology (11 Mar 2008)