Definition of Dedifferentiate

1. Verb. Lose specialization in form or function.

Generic synonyms: Develop
Derivative terms: Dedifferentiation
Antonyms: Differentiate

Definition of Dedifferentiate

1. Verb. To lose or reverse differentiation ¹

¹ Source: wiktionary.com

Definition of Dedifferentiate

1. [v -ATED, -ATING, -ATES]

Medical Definition of Dedifferentiate

1. A mature cell returning to a less mature state. See: differentiate, undifferentiated. (16 Dec 1997)

Lexicographical Neighbors of Dedifferentiate

dedicate
dedicated
dedicated file server
dedicatedly
dedicatee
dedicatees
dedicates
dedicating
dedication
dedications
dedicator
dedicatorial
dedicatories
dedicators
dedicatory
dedifferentiate (current term)
dedifferentiated
dedifferentiates
dedifferentiating
dedifferentiations
dedimus
dedimuses
dedisperse
dedispersed
dedispersing
dedition
deditions
dedolation
dedovshchina

Literary usage of Dedifferentiate

Below you will find example usage of this term as found in modern and/or classical literature:

1. Biological Bulletin by Marine Biological Laboratory (Woods Hole, Mass.) (1912)
"... may arise from parts which have already undergone some degree of differentiation, but which under altered conditions dedifferentiate and produce buds. ..."

2. An Introduction to Cytology by Lester Whyland Sharp (1921)
"In the lower organisms cell differentiation in this sense is not so great but that almost any cell may retain the power to "dedifferentiate" and begin the ..."

3. The Journal of Heredity by American Genetic Association (1917)
"... revert to the embryonic type—dedifferentiate as Child puts it—and from this embryonic type go on to reproduce the whole new organism. ..."

4. The Journal of Experimental Medicine by Rockefeller University, Rockefeller Institute, Rockefeller Institute for Medical Research (1922)
"The epithelial cells did not dedifferentiate. Although the strain is 3 months old, they grow as a pavement membrane and have kept their epithelial ..."

5. Individuality in Organisms by Charles Manning Child (1915)
"The cells of x are so extremely affected by the presence of the wound and the altered conditions that they rapidly dedifferentiate and begin to divide and ..."

6. Reviews in Environmental Health (1998): Toxicological Defense Mechanics edited by Gary E. R. Hook, George W. Lucier (2000)
"... increase tyrosine hydroxylase (TH) activity, and dedifferentiate with the removal of such growth factors [for review see Fujita et al. (109)}. ..."

7. Architectural Bodies by Ad Graafland, Michael Speaks (1996)
"In order to cope with these proprioceptive-exteroceptive stimuli the psychotic ego tries to dedifferentiate, ..."

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