Medical Definition of Cytochrome p-450 cyp1a2
1.
A polycyclic aromatic hydrocarbon-inducible cytochrome which is of significant clinical interest due to the large number of drug interactions associated with induction and inhibition of theophylline. Caffeine is considered to be a model substrate for this enzyme. It also metabolises theophylline and antipyrene. Environmental factors including cigarette smoking, charbroiled meat, cruciferous vegetables, and a number of drugs including phenytoin, phenobarbital, and omeprazole produce increases in cyp1a2 activity.
Registry number: EC 1.-
(12 Dec 1998)
Lexicographical Neighbors of Cytochrome P-450 Cyp1a2
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