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Definition of Cytochalasin
1. Noun. (biochemistry) Any of several related fungal metabolites that have an effect on cytokinesis while not affecting karyokinesis ¹
¹ Source: wiktionary.com
Definition of Cytochalasin
1. [n -S]
Medical Definition of Cytochalasin
1. A group of fungal metabolites that inhibit the addition of G actin to a nucleation site and therefore perturb labile microfilament arrays. Cytochalasin B inhibits at around 1 microgram/ml but at about 5 _g/ml begins to inhibit glucose transport. Cytochalasin D affects only the microfilament system and is therefore preferable. This entry appears with permission from the Dictionary of Cell and Molecular Biology (11 Mar 2008)
Lexicographical Neighbors of Cytochalasin
Literary usage of Cytochalasin
Below you will find example usage of this term as found in modern and/or classical literature:
1. Proceedings of the Society for Experimental Biology and Medicine (1903)
"As asly reported, cytochalasin B induced i capping in alveolar macrophages, ...
1, cytochalasin B prevented colchicine-induced Con A capping in both the ..."
2. Pathogens of Soybean Seeds: Bibliographyby Andrew Kalinski by Andrew Kalinski (1999)
"Toxic, cytochalasin-like compounds from Macrophomina phaseolina. Phytopathology
79:1166. PB: 9001 TO 9012 BEKELE, E. 1990. FHB of wheat and Fusarium toxins ..."
3. A Lifelong Passion: Nicholas and Alexandra: Their Own Story by Andrei Maylunas (2005)
"... with phorbol myristate acetate (PMA) and FMLP with cytochalasin В (FMLP/CB)
were measured prior to the administration of the antioxidant/placebo after 4 ..."
4. Anabolic Steroid Abuse by Geraline C. Lin (1996)
"... and the primary defect appears to be a disruption of microfilaments similar
to the action produced with cytochalasin B (Phillips et al. 1978). ..."
5. Reviews in Environmental Health (1998): Toxicological Defense Mechanics edited by Gary E. R. Hook, George W. Lucier (2000)
"In these studies cytochalasin D, an inhibitor of microfila- ment assembly, did
not influence TNF- mediated IL-8 release but substantially inhibited ..."