|
Definition of Cytochalasin
1. [n -S]
Medical Definition of Cytochalasin
1. A group of fungal metabolites that inhibit the addition of G actin to a nucleation site and therefore perturb labile microfilament arrays. Cytochalasin B inhibits at around 1 microgram/ml but at about 5 _g/ml begins to inhibit glucose transport. Cytochalasin D affects only the microfilament system and is therefore preferable. This entry appears with permission from the Dictionary of Cell and Molecular Biology (11 Mar 2008)