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Medical Definition of Cpg islands
1. Areas of increased density of the dinucleotide sequence guanine--phosphate diester--cytosine. They form stretches of DNA several hundred base pairs long and number about 30,000 islands in the mammalian genome. They are unmethylated and the site of frequent mutations. Many of the genes with which the islands are associated are housekeeping genes that are constitutively expressed. (12 Dec 1998)
Lexicographical Neighbors of Cpg Islands
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