|
Medical Definition of Contact inhibition of movement
1. Reaction in which the direction of motion of a cell is altered following collision with another cell. In heterologous contacts both cell may respond (mutual inhibition) or only one (nonreciprocal). Type I contact inhibition involves paralysis of the locomotory machinery, Type II is a consequence of adhesive preference for the substratum rather than the dorsal surface of the other cell. This entry appears with permission from the Dictionary of Cell and Molecular Biology (11 Mar 2008)