1. Intrauterine bone dysplasia and synostosis of the coronal and lambdoid sutures producing a trilobar head shape, due to premature fusion (craniosynostosis) of all sutures.
This produces various craniofacial and long-bone anomalies. The condition is sporadic; no evidence to suggest a genetic cause although there may be some hereditary in Crouzon syndrome.
(20 Jun 2000)