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Medical Definition of Circumventricular organs
1. Four small areas in or near the base of the brain that have fenestrated capillaries and are outside the blood-brain barrier. They are neurohypophysis, area postrema, organum vasculosum of the lamina terminalis and subfornical organ (SFO). The neurohypophysis is a neurohemal organ. The other three are chemoreceptors: area postrema triggers vomiting in response to chemical changes in plasma, organum vasculosum of the lamina terminalis senses osmolality and alters vasopressin secretion and SFO initiates drinking in response to angiotensin II. (05 Mar 2000)