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Definition of Chromosomal mutation
1. Noun. (genetics) any event that changes genetic structure; any alteration in the inherited nucleic acid sequence of the genotype of an organism.
Category relationships: Genetic Science, Genetics
Generic synonyms: Alteration, Change, Modification
Specialized synonyms: Deletion, Inversion, Transposition, Gene Mutation, Point Mutation, Reversion, Saltation
Terms within: Mutagenesis
Derivative terms: Mutate, Mutational
Medical Definition of Chromosomal mutation
1. Can refer to any of a number of DNA mutations which results in a change in the protein encoded by the mutated gene, such as point mutations, insertion or deletion mutations (frameshift mutations), or nonsense mutations. More often this refers to mutations involving chromosomes, such as the inversion of part of one chromosome such that the inverted part no longer matches with its homologous pair, a translocation of one part of a chromosome to a different chromosome, deletions of parts of chromosomes, or accidents which happen during the division of the nucleus like the unequal portioning of chromosomes between the daughter cells. (09 Oct 1997)
Lexicographical Neighbors of Chromosomal Mutation
Literary usage of Chromosomal mutation
Below you will find example usage of this term as found in modern and/or classical literature:
1. Reviews in Environmental Health (1998): Toxicological Defense Mechanics edited by Gary E. R. Hook, George W. Lucier (2000)
"... the impact of a gene or chromosomal mutation or the death of a cell or an
activated gene also depends on the type of cell in which these events occur ..."
2. Risk Analysis: A Guide to Principles and Methods for Analyzing Health and by John J. Cohrssen, Vincent T. Covello (1989)
"As described in Chapter 1. the induction of cancer may have many potential
mechanisms (gene or chromosomal mutation, heritable changes in DNA transcription ..."
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