Lexic.us

Definition of Christmas disease

1. Noun. A clotting disorder similar to hemophilia A but caused by a congenital deficiency of factor IX.

Definition of Christmas disease

1. Noun. (idiomatic) haemophilia B ¹

¹ Source: wiktionary.com

Medical Definition of Christmas disease

1. A form of haemophilia in males that results from a deficiency of clotting factor IX, transmitted as a X-linked trait (first described in the Christmas issue of British Medical Journal in 1952). Inherited in similar sex-linked way to classical haemophilia. Symptoms include easy bruising, nosebleeds, bleeding gums and bleeding into muscle tissue (haematoma) or a joint space (haemarthrosis). Treatment includes the infusion of factor IX concentrates to normalize blood coagulation. Inheritance: sex-linked (X chromosome). (27 Sep 1997)

Lexicographical Neighbors of Christmas Disease

Literary usage of Christmas disease

Below you will find example usage of this term as found in modern and/or classical literature:

1. Handbook of Severe Disability: A Text for Rehabilitation Counselors, Other edited by Walter C. Stolov, Michael R. Clowers (2000)
"... is the most common, accounting for 75-80 percent of hemophiliacs. Hemophilia B, also known as christmas disease or factor IX deficiency, ..."

2. Old Man Dare's Talk to College Men by Howard Bement (1922)
"The square, manly shoulders drooped, and the boy's whole attitude became devil-may-care. He went home before Christmas, disease-ridden, ..."

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