Definition of Chaperone
1. Noun. One who accompanies and supervises a young woman or gatherings of young people.
2. Verb. Accompany as a chaperone.
Definition of Chaperone
1. [v -ONED, -ONING, -ONES]
Medical Definition of Chaperone
1.
| Cytoplasmic proteins of both prokaryotes and eukaryotes that bind to nascent or unfolded polypeptides and ensure correct folding or transport. Chaperone proteins do not covalently bind to their targets and do not form part of the finished product. Heat-shock proteins are an important sub set of chaperones. Three major families are recognised, the chaperonins (groEL and hsp60), the hsp70 family and the hsp90 family. Outside these major families are other proteins with similar functions including nucleoplasmin, secB and T-cell receptor associated protein.
This entry appears with permission from the Dictionary of Cell and Molecular Biology
(11 Mar 2008)
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Lexicographical Neighbors of Chaperone
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