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Medical Definition of Cerebral gigantism
1. A syndrome characterised by increased birth weight and length (above 90th percentile), accelerated growth rate for the first 4 or 5 years without elevation of serum growth hormone levels, and then reversion to normal growth rate; characteristic facies include prognathism, hypertelorism, antimongoloid slant, and dolichocephalic skull; moderate mental retardation and impaired coordination are also associated. See: Sotos' syndrome. (05 Mar 2000)